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Obesity is one of the most common disorders and a serious world wide health problem because of its association with other pathologies. The attendance rate of obesity has increased in the last century, particularly in the last decades, having already been considered by WHO as the XXI century epidemic. Overweight/Obesity is the result of the interaction between genetic and environmental factors. Only a small number of cases is due to other causes (endocrine pathologies, tumors and others). The genetic component that contributes to obesity is multifactorial, involving several genes and polymorphisms. Overweight/Obesity is a chronic condition associated with an increased risk of hypertension,type II diabetes, cardiovascular disease and various types of cancers. Genetics has been anextremely useful tool to understanding this disease. There are several important genes onthe development of overweight/obesity that are described in several association studies that establish a relationship between phenotype / genotype. Nowadays, the diagnosis of obesity is made by anthropometric factors such as, body massindex (BMI) and waist circumference, not taking into account genetic and endocrine factors leading to the pathology development, especially in individuals with family history. DNA and/or RNA molecular detection could help in the characterization of genetic changes (mutations/polymorphisms) involved in this pathology. STAB VIDA is one of the pioneers in this area, having already contributed to thedevelopment of new technologies through a kit to obesity predisposition and relateddiseases by DNA direct sequencing method.
